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The GEMINI study showed that carvedilol affects glucose metabolism more favorably than metoprolol
Many consumers discontinue or cycle off GLP-1 medications due to tolerability issues, side effects, or the challenges of staying on therapy indefinitely

The Index date was set as the first prescription of GLP-1 RA, SGLT-2 inhibitors or DPP-4 inhibitors

Pregnancy: Avoid use during pregnancy or for women planning conception within 2 months

For longitudinal research and multi-condition assays, its a structural advantage
