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Jackson Laboratories) were fed standard chow diet (Tekland Global Diet 2920X

The results demonstrated a dose-dependent effect on weight loss, with the maximum reduction reaching 14.7%, compared to only 2.3% in the placebo group

[DOI] [PubMed] [Google Scholar] 9.Sattar N., Lee M.M.Y., Kristensen S.L., Branch K.R.H., Del Prato S., Khurmi N.S., Lam C.S.P., Lopes R.D., McMurray J.J.V., Pratley R.E., et al

Some people prefer an overlap approach, where they start retatrutide at a low dose while tapering off their previous medication

Ozempic prescribing information and Instructions for Use, revised November 2024