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For astrocytes, GLP-1R activation prevents conversion to neurotoxic A1 phenotypes by interrupting microglia-derived IL-1/TNF-/C1q signaling [24,47,48], thereby promoting amyloid- clearance in Alzheimer's disease models [48] and pathogenic -synuclein in PD models [47]

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American Psychological Association

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How Serena Williams admission of using a GLP-1 drug could impact the stigma of obesity Serena Williams GLP-1 disclosure may shift obesity conversations, though treatment requires a holistic approach, Northeastern experts say