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16 , 44 , 45 However, the consequences of treatment withdrawal remain largely uncharacterized, underscoring the need for longitudinal studies on potential rebound risks
Clinical trial participants on the highest dose recorded an average weight loss of 12.4% when combined with lifestyle modification
Lin CY, et al
Strategies such as gradual drug titration, understanding drugtarget interactions for repurposing, system-wide approaches in drug development, optimized dosing, and improved drug delivery systems are all aimed at reducing these side effects [19]
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