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By 48 weeks, more than 90% had resolved their steatosis entirely

These acts of self-regulation can be seen as an attempt by patients to achieve a personal balance between efficacy and negative effects

Although central activity is likely to contribute to visceral hypersensitivity, peripheral factors, including immune, paracrine and endocrine molecules, are also likely to play a role in the sensitisation of gut-to-brain signalling in IBS

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