semaglutide colon cancer GLP-1 Weight-Loss Meds Linked to Improved Survival Emerging Evidence Positions GLP-1 Receptor

The folate supplement L-methylfolate (Deplin, 7.515 mg/day) is FDA approved as a medical food for antidepressant augmentation, which is a less rigorous standard than approval as a medication

Direct head-to-head comparison of tirzepatide vs semaglutide was conducted in the SURPASS-2 trial, which showed tirzepatide 15mg weekly produced significantly greater HbA1c reduction (-2.46% vs -1.86%) and weight loss (-12.4 kg vs -6.2 kg) compared to semaglutide 1mg weekly in type 2 diabetes

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The primary outcome was the daily differences in time in range (TIR) (3.9-10.0 mmol/l) between arms

Do not use Trulicity if you or any of your family have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC), or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)