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Our previous studies have demonstrated that exendin-4 therapy can protect the kidneys and preserve renal function in response to ischemia-reperfusion injury by upregulating antioxidants, and reducing inflammation, oxidative stress and fibrosis (30-34)

They observed, however, that this only happened in 'the presence of supra-fasting blood glucose levels or well fed individuals'

History of pancreatitis is a relative contraindication

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In cases where TFF alone doesnt achieve the required concentration, operators may leverage thin film evaporation, which further concentrates the solution while minimizing its exposure to heat