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Like many medications, the effectiveness of retatrutide depends heavily on the correct dosage

Future randomised controlled trials should specifically evaluate the effectiveness of novel AOMs for long-term weight management in older adults with obesity, carefully considering the impact on body composition and functional ability, as well as health economics.
PlexusDx explains the clinical reasons behind dose titration and how this approach maximizes weight loss while minimizing side effects

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Accessed October 30, 2025
