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However, previous studies have found that DPP-4 can be regulated by inflammatory factors such as signal transducer and activator of transcription 1 (STAT1), hepatocyte nuclear factor-1 (HNF-1), interleukin-12 (IL-12), and tumor necrosis factor- (TNF-) [33,34,35]

Although these findings offer reassurance regarding the safety of these drugs, further validation is essential

The World Health Organization (WHO) defines both overweight and obesity as abnormal or excessive fat accumulation that presents a risk to health

Annals of medicine

PMID: 28781108 (This report is OPEN ACCESS if you would like to read it) In the study, the investigators recruited 62 people with Parkinsons (average time since diagnosis was approximately 6 years) and they randomly assigned them to one of two groups, exenatide (the Bydureon formulation which is injected once per week) or placebo (32 and 30 people, respectively)