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Slows Gastric Emptying GLP-1 medications slow the rate at which the stomach empties, suppressing appetite and leading to subsequent weight loss

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When starting GLP-1 medications, doctors usually begin with a low dose and increase it slowly over several weeks or months to reduce side effects, especially nausea and stomach upset

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In summary, GLP-1 or GLP-1RA treatment can make a positive impact on reducing the impact of hypertension in affected patients (Figure 1)

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Preclinical evidence suggests that increasing protein intake may offset circulating amino-acids reduction, however this may also blunt the increase in whole-body energy expenditure [63]

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This new HFpEF paradigm thus shifts the focus from LV afterload excess to coronary microvascular inflammation

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