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Thus, there is a highly unmet medical need to ameliorate hyperphagia and obesity related to POMC-MC4R pathway deficiency

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However, exendin-4 does not change the membrane potential as well as the firing rate of melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus (Acuna-Goycolea and van den Pol, 2004)

Researchers dont yet know exactly why Zoloft and other depressants can cause weight gain for some people
