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Semaglutide showed fewer serious adverse events compared to placebo in long-term studies

What the studies have flagged so far

However, the complexity of targeting central mechanisms contributes to significant side effect profiles that have limited long-term and widescale use of these medications for obesity indications

Patients prescribed Ozempic typically start on a lower dose (0.25 mg weekly) which is gradually increased to therapeutic levels (0.5 mg, 1 mg, or 2 mg weekly) at 4-week intervals based on glycaemic response and tolerability