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Yes, but the transition should be guided by a healthcare provider, not by direct dose matching
Evidence from a multicenter, long-term cardiovascular outcome trial demonstrated that GLP-1RAs reduce mortality associated with cardiovascular disease and confer protective effects by decreasing the incidence of myocardial infarction and nonfatal stroke.104 GLP-1RAs have been shown to enhance endothelial cell function through anti-inflammatory and vasodilatory mechanisms

doi: 10.1007/s40618-021-01574-9 17 PurtellLSzeLLoughnanGSmithEHerzogHSainsburyAet al

The pharmacokinetic half-life of semaglutide is approximately 168 hours, or one week
Some improvements in insulin sensitivity and inflammatory markers can begin emerging within 4 to 8 weeks of treatment Leptin normalization, however, follows actual fat mass reduction rather than drug exposure directly, meaning those benefits likely take months of sustained treatment