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Some injections are also thought to potentially increase the risk for inflammation of the pancreas

Rotate injection sites (abdomen, thigh, or upper arm) to reduce injection site reactions

Emerging evidence suggests that these drugs, due to their ability to access the circumventricular organs such as the area postrema, a brain region involved in nausea responses may trigger this adverse effect
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Those with genetic predispositions toward stronger hunger signals may experience faster regain and more intense cravings during brief treatment interruptions
