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Collectively, these findings indicate that activation of GLP-1-producing neurons in the NTS attenuates cocaine seeking and regulates the mesolimbic dopamine system via direct projections to the VTA as well as polysynaptic connections to the VTA via GLP-1R-expressing hubs such as the LDTg

Ozempic is also prescribed for weight loss, which is considered an off-label treatment rarely covered by insurance

The third limitation is that there may be the potential for numerous indirect effects or confounding

MAN has been member on advisory boards or has consulted with AstraZeneca, Boehringer Ingelheim, Eli Lilly, Fractyl, GlaxoSmithKline, Menarini/Berlin Chemie, Merck, Sharp & Dohme, and Novo Nordisk