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Diabetes 73 , 292305 (2024)

doi: 10.1007/BF00577838

Correlations were calculated for each of the 500 complete multiple imputed datasets for body weight, HbA 1c and systolic and diastolic BP and combined using Rubins rules [27]

This suggests that either the side effects were manageable enough to tolerate, or that the visible results motivated continued use through uncomfortable periods
