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However, the EMPA-REG OUTCOME trial with empagliflozin, the DECLARE-TIMI 58 trial with dapagliflozin, and the VERTIS CV trial with ertuglifozin did not report an increase in amputations in the patients treated with an SGLT2 inhibitor (143,156,160,230)
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RELATED: Popular weight-loss and diabetes medications linked to lower risk of some cancers, study finds "One of the challenges that we have as clinicians is we know that some of these benefits help patients
Dandona P, Ghanim H, Chaudhuri A
Because diabetes can damage blood vessels, cause high blood pressure and increase the risk for heart attack and heart failure, improving blood sugar can help prevent all of these downstream effects
