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The development of these agents underscores the continuous improvement of the pharmacokinetic and pharmacodynamic profiles of these peptide agents [ Table 1 ], expanding their applications beyond T2DM and obesity to encompass cardiovascular disease event reduction [ Table 2 ]

32,107,234 Interestingly, in contrast to this, a recent study concluded that central and peripheral GLP-1 systems suppress eating via independent gut-brain circuits in mice

This underlying diversity in techniques, patient demographics, and data collecting methods, thereby impacting the consistency of findings and the generalizability of our results

But those studies have been small and often limited to one substance