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Marso SP, Bain SC, Consoli A, Eliaschewitz FG, Jdar E, Leiter LA, Lingvay I, Rosenstock J, Seufert J, Warren ML, et al

One thing researchers cannot yet answer is what would happen to patients who stopped taking a GLP-1

Tirzepatide which targets both GLP-1 and GIP receptors has shown even more dramatic early results: weight loss of 1020 kg and insulin dose reductions exceeding 30% in observational and phase 2 data, with improved CGM time in range
New Weight Loss Medications There is now an entirely new class of weight loss medications that work in a different mechanism of action than others

This discovery provides an essential mechanistic blueprint to explain why patient responses vary, why weight loss eventually plateaus, and how combining treatments could extend drug efficacy
