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This proactive assessment helps identify potential risks early

Sensory gating theory explains it

This timeline allows for stable establishment of probiotic strains, consistent production of bacterial metabolites, time for downstream metabolic effects to potentially emerge, and enough consistency to assess subjective changes in appetite, energy, and wellbeing

The assessment includes automatic exclusionary screening for absolute contraindications that would prevent safe GLP-1 use

Covariates We selected covariates assumed to be associated with selection of patients for GLP-1 RAs, SGLT-2 inhibitors, DPP-4 inhibitors and risk of suicide or suicide attempts from the Danish National Patient Registry and Danish National Prescription Registry