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The key point is that this is the first randomized, placebo-controlled clinical evidence that a GLP-1 receptor agonist may slow the biological processes associated with aging in humans. Michael Corley, PhD Using multiple epigenetic clocks, we saw a broad pattern of slower biological aging in participants treated with semaglutide compared with placebo, including a 9% slowing in the pace of aging measured by DunedinPACE and a significant effect on PCGrimAge, which tracks processes linked to all-cause mortality and age-related disease, the researcher detailed

this result was observed regardless of baseline CV risk profile, with no significant differences between subgroups (p = 0.25 for interaction between subjects with prior MI or stroke vs no prior MI or stroke and p = 0.27 for interaction between subjects with established CVD vs CV risk factors only)

In this study, the proportion of subjects with severe hypoglycemia and hypoglycemia was similar between the two treatment arms

Skipping breakfast might seem tempting, but a light, well-balanced meal helps: Support steady energy levels Prevent nausea, a common side effect of GLP-1s Reduce mid-morning cravings Maintain muscle mass while losing weight Choosing the right foods in the morning sets the tone for your whole day