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This framework integrated evidence through the following streams: (1) Tirzepatide compared to placebo (indirect comparison): In the absence of direct tirzepatide CV outcome placebo-controlled trials, these estimates were derived by bridging direct evidence from SURPASS-CVOT with pooled data from multiple GLP-1RA-placebo trials

doi:10.1111/j.1365-2249.2012.04646

Store the medication according to label instructions

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