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Antidepressants and anticholinergics Anticholinergic medications, including many antidepressants, antihistamines, and bladder medications, cause dry mouth by directly blocking the nerve signals that stimulate saliva production

In such circumstances: Contact emergency services (999) or attend the nearest Accident & Emergency department Call NHS 111 for urgent but non-life-threatening concerns Contact your local NHS urgent mental health helpline (search online for 'NHS urgent mental health helpline' and your location) Call the Samaritans (116 123, available 24/7) for immediate emotional support Do not leave the person alone if they are at immediate risk For non-emergency concerns about mood changes whilst taking GLP-1 agonists, patients should contact their GP or diabetes specialist nurse within 2448 hours

The total annual number of events was calculated by summing events from both abovementioned groups

The CCA for the remaining meta-analyses was 2%, indicating a slight level of overlap

These arent just metabolic medications that happen to help with weight