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Acute pancreatitis has been reported in connection with GLP-1 RAs use [121, 124,125,126], though the data are insufficient to establish a causal relationship

The GLP-1R/GcgR dual agonist Bamadutide, SAR425899, underwent a phase I single- and multiple-ascending-dose clinical trial with daily subcutaneous administration in both healthy/overweight subjects and overweight/obese patients with T2DM

11 However, human data remains largely inconclusive, necessitating additional research to establish efficacy and optimal dosage

B.KlibanskiA.et al (2009)

When uncontrolled diabetes is reported, the assessment must state hypoglycemia or hyperglycemia to assign a code other than diabetes without complications, and must include clinical documentation supporting the diagnosis.Use one of the five categories to identify the clinical manifestation:E08 - DM - due to underlying conditionE09 - Drug- or chemical-induced DME10 - Type 1 DME11 - Type 2 DME13 - Other specified DMUse a third character to denote the type of DM (e.g., Type 1 or Type 2)Use a fourth character to denote the type of DM complicationUse a fifth and sixth character to denote the subclassification of the body system complicationIn most cases, a single combination code reports both the DM and the complicationFollow additional code instructions for CKD stage, glaucoma and ulcer site complicationCurrent or long-term use of insulin should be coded as Z79.4Complications and ManifestationsAll DM manifestations should be documented with specific details of complications