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The point here isn't that Zevay's process is flawed

IHC with an antibody recognizing mouse and rat GLP-1R showed expression in cultured tanycytes, whereas no signal was seen in endothelial cells isolated from rat cortices or in secondary antibody controls (Supplemental Figure 4)

For q2wk dosing, the model predicts steady state body weight changes of 12%, 16%, and 18% for tirzepatide at 5 mg, 10 mg, and 15 mg, respectively

This difference may influence your choice, especially if achieving maximum weight loss is a priority

More widespread use could reduce the stigma around GLP-1 use Millions more people going on GLP-1s could also alter one of the defining features of the recent weight-loss boom: the stigma that some people still experience for using one of these drugs