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One 2024 study at the Smell and Taste Center at the University of Pennsylvania (source) found evidence of GLP1 agonists significantly depressing the perception of all five basic taste qualities. Interestingly, while all participants in the study experienced a slight decline in their sense of smell, it was not considered statistically significant suggesting that olfactory changes may be more individualised, or more complex to detect in standardised tests

Many patients who hit a plateau also realize they may need to refine their technique or expectations

Nevertheless, it is important that you know the signs and symptoms to look out for

[1] [11] While there is no evidence that Ozempic worsens heart failure, the limited data in patients with advanced cardiac dysfunction means treatment decisions should involve cardiology input and individualised risk-benefit assessment

Semaglutide is an injection, not an oral medication, so meal timing does not directly affect absorption