itchy at injection site tirzepatide & Zepbound Rash and Injection-Site Reactions: Causes, Treatment, and Prevention How to Use Mounjaro: Injection

FDAs Purple Book for biologics and public ANDA database for small molecules contain this information

For the majority, symptoms improve significantly by weeks 8 to 12 as the body adapts to the medication

10.1186/s12902-015-0044-z [DOI] [PMC free article] [PubMed] [Google Scholar] 4.Mendivil CO, Mrquez-Rodrguez E, ngel ID, et al

Although initially heralded as a cure for blood cancers, researchers have suggested that it could have a lasting impact on other conditions such as heart disease and autoimmunity

People knew they caused weight loss, but the pharmaceutical companies werent allowed to market weight loss as an indication, so weight loss had to be listed as an adverse effect with possible beneficial implications