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Rare: may affect up to 1 in 1,000 people : Severe allergic reactions (anaphylactic reactions, angioedema)

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The injection is performed just once a week and the dose is gradually increased over several weeks

Tirzepatide is the first dual long-acting glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonist indicated for the treatment of type 2 diabetes in adults, for reducing excess body weight and maintaining long-term weight reduction in adults with obesity or overweight and at least one weight-related comorbid condition, and for treating obstructive sleep apnea in adults with obesity