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When orally administered, glutamine also increases circulating GLP-1 and insulin in lean, obese and type-2 diabetic individuals [307]

Blackwell J, Saxena S, Jayasooriya N, et al

A review of current guidelines for the treatment of obesity

A 28-day, MAD phase 1 trial shows mean weight loss of 2.1%, 0.3%, 0.9%, 1.1%, 3.2% and 5.3% for placebo and target doses of 2.5 mg, 5 mg, 10 mg, 20 mg, and 40 mg, respectively (65)

a Effectiveness is based on average excess weight loss (EWL) or total body weight loss (TBWL) over the indicated time period
