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(3) studies that did not report the change in weight after treatment discontinuation

This mitigates sharp post-meal spikes in blood sugar, promoting more stable glucose levels throughout the day

Multi-District Litigation Wherein a class action lawsuit, a single lawsuit is filed on behalf of a group of people who have suffered similar harm or injuries, multi-district litigation (MDL) involves the consolidation of multiple civil cases that share common questions of fact and involve similar defendants, but where the individual circumstances of each case may differ

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Overall, the effect of GLP-1RAs on muscle mass shows a high degree of heterogeneity in clinical trials: some studies report that lean body mass reduction accounts for 40% to 60% of total weight loss, while others indicate that the proportion of lean body mass reduction is approximately 15% or lower [50]