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Maiorov, V

An Oxford study revealed that taking the GLP-1 drug had no increased risk of adverse neurological or psychiatric outcomes compared to other antidiabetic medications

Clinical studies have not established decreased libido as an official side effect, but the emerging case report literature and proposed neurochemical mechanisms suggest it occurs in a subset of women

When energy availability drops, AMPK switches on and signals cells to shift into a more efficient energy-using mode

Specifically, the use of GLP-1RAs results in a reduction in BP (reduction in systolic BP by 1 mmHg with lixisenatide and by 5.4 mmHg with semaglutide) through a natriuretic and vasodilatory effect, likely mediated by the atrial natriuretic peptide, released as a result of binding to specific receptors expressed in the atria [43]