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A practical approach: eat your normal reduced calories 5 days per week

Rare but serious side effects include pancreatitis (severe abdominal pain), gallbladder problems (upper right abdominal pain after eating), or thyroid concernsespecially in patients with a personal or family history of medullary thyroid cancer

Protocol-specified discontinuation criteria include safety concerns from the investigator, calcitonin level 100 ng/L, suspicion of pancreatitis, pregnancy or intention to become preg- nant, and participation in another clinical trial

Interestingly, these patterns in levels of amino acids correlated with changes in both insulin secretion and insulin sensitivity