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Lower induction doses (0.25 mg) produce gentler effects, allowing your body to adjust while minimizing nausea and gastrointestinal side effects, whereas patients tolerating rapid titration may see sharper appetite reduction and faster initial weight loss

Studies from the New England Journal of Medicine documented that people who discontinued semaglutide gained back an average of two-thirds of their weight within 12 months, even with continued diet and exercise efforts

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