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These data underline a critical truth: GLP-1 receptor agonists behave like chronic disease treatments

Blocking was performed with 2% donkey serum in PBS at 37 C for 15 min, and the sample was then rinsed twice with 0.2% bovine serum albumin (BSA) in PBS

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Under repeated insult or injury, mTORC1 becomes constitutively active, triggering an irreversible return to stemness, cell division, proliferation, and inflammation among dedifferentiated epithelial cells

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