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Description
current UK anaesthetic guidance advises holding GLP-1 receptor agonists for 12 weeks before surgery due to delayed gastric emptying and aspiration risk Patients should be counselled that weight loss may be slower or temporarily plateau during corticosteroid treatment, but this does not necessarily mean Wegovy should be discontinued

Both acute and 4-hour exposure to GLP-1 slowed gastric emptying markedly, but the degree of deceleration was less for the second meal

More than half (52%) of GLP-1 users described their eating habits as "mindful", saying they are increasingly guided by hunger cues rather than established routines or restrictive dieting practices

While the hazard ratio (HR) was 1.60, the absolute numbers were small (3% vs 0.5%)

Yes, GLP-1 receptors in the ventral tegmental area and nucleus accumbens modulate dopamine signaling in the mesolimbic reward system
