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47,48 These synthetic protein preparations exhibit partial or complete amino acid sequence homology with endogenous GLP-1, rendering them resistant to degradation which resulting in a prolonged half-life and heightened biological activity

NIDA is sponsoring a randomized clinical trial with the "twincretin" Tirzepatide for cannabis use disorder

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Here are the drugs they reviewed: Other conditions now being evaluated for GLP-1 effectiveness include: Parkinsons Disease Alzheimers dementia Alcohol use disorder These drugs are also being evaluated for obsessive-compulsive disorder, opioid use disorder, gambling, and other mental health diagnoses, although these are not mentioned in this review