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BMI 27 with weight-related conditions, such as: Type 2 diabetes or prediabetes Hypertension High cholesterol Sleep apnea Fatty liver disease (NAFLD) PCOS Insulin resistance Patients in this range may be candidates because GLP-1 medications act on pathways related to blood sugar, appetite, and metabolic regulation

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It is likely that insurers, and Medicare, will revise their coverage on the basis of the trial to cover the drug for high-risk patients that fit the entry criteria of the trial, but that will represent a very large economic burden to cover the drug cost
Your medical profile is the primary consideration
