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Acknowledgments We thank Chih-Shung Wongs research assistants, Ching-Pai Wang and Tsou-Mei Liu, for performing animal drug administration and organ dissection for the studies

Animal care and experimental procedures adhered to the binding European standards for research on animal models (Act from January 15, 2015, on the Protection of Animals, Used for Scientific or Educational Purposes

coli translocation via PCR and showed that liraglutide-treated mice had significantly higher BT rates compared to controls

A healthcare provider helps ensure: Appropriate patient selection based on BMI, medical history, and metabolic risk factors Safe dose escalation , reducing the likelihood of gastrointestinal side effects Monitoring for contraindications , including thyroid conditions or pancreatitis risk Assessment of treatment response , including weight trends and metabolic markers Long-term planning , as Wegovy is designed for chronic weight management rather than short-term use Without medical oversight, patients may misuse dosing schedules, discontinue treatment prematurely, or overlook side effects that require adjustment