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Why added sugar impacts GLP-1 Interestingly, research suggests that diets high in added sugars may reduce natural GLP-1 secretion (1)

In a 6-month randomized, placebo-controlled trial in adults with BMI 28-34.9 (N=225), post-hoc factorial analysis found a B420-associated -4.0% difference in body fat mass (P=0.002), approximately 2.4 cm greater waist-circumference reduction, and roughly 300 kcal/day greater reduction in energy intake versus placebo

They follow total fat and lean mass changes over time using DEXA (dual-energy X-ray absorptiometry) scans

Storage temperature exceeded if the medication has been exposed to temperatures above the product-specific limit (check your leaflet/SmPC) for extended periods, it should be discarded