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[DOI] [PubMed] [Google Scholar] 6.Utzschneider KM and Kahn SE, Review: The Role of Insulin Resistance in Nonalcoholic Fatty Liver Disease, Journal of Clinical Endocrinology and Metabolism 91, no

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The eGFR slope improved from a median of 2.37 mL/min/1.73 m 2 per year before treatment to +0.49 mL/min/1.73 m 2 per year during treatment, indicating significant renoprotective benefits [183]

Of these 50 semaglutide-treated patients that developed anti-semaglutide antibodies, 28 patients (1.6% of the overall population) developed antibodies cross-reacting with native GLP-1.The in vitro neutralizing activity of the antibodies is uncertain at this time