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Patients who achieve remission of obesity-related conditions like sleep apnea or fatty liver disease may feel motivated to continue therapy

35 Preserving muscle mass during weight loss is crucial for several reasons: muscle tissue is metabolically active (burning more calories at rest than fat), contributes to strength and physical function, supports bone density, and helps prevent the metabolic slowdown that can lead to weight regain after stopping medication or reaching a plateau

The onset of reactions varied, occurring between 4 weeks and 3 years after medication initiation

Comparing annual costs against expected outcomes provides a more realistic perspective

This combination of physical barriers and psychological stress creates a discouraging cycle, making sustainable weight loss feel almost unattainable