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Description
When GIPR-Ab/GLP- 1 is used instead of GIPR-Ab or a control antibody conjugate, the body weight loss is higher, indicating synergistic effects
The dual control of insulin secretion by glucose involves triggering and amplifying pathways in beta-cells
Fact : The drugs efficacy varies from person to person
Research is limited, but so far, that doesnt seem to be the case
Previous inactive GLP-1R TMD structures revealed how allosteric modulators can precisely regulate its function from the extra-helical binding sites 13
