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Valentine, V., Goldman, J

Yes, PlexusDx Precision Peptide Genetic Test ($99 add-on) identifies genetic variants in GLP1R, GIPR, FTO, and MC4R that influence metabolic stress, fluid handling, and inflammationall relevant to kidney health

These targeted treatments regulate key functions such as appetite control, metabolism, energy levels, and hormone balance

The TRIUMPH-4 osteoarthritis data a reminder One thing worth flagging from TRIUMPH-4 (published December 2025), because it gets less coverage than the weight-loss numbers: in participants with obesity and knee osteoarthritis, retatrutide 12 mg produced an average 75.8% reduction in WOMAC pain scores , with more than one in eight participants ending the trial completely free of knee pain
Mild sleep apnea is different from moderate-to-severe OSA
