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Additionally, GLP-1 promotes the growth and proliferation of pancreatic cells, inhibits glucagon secretion, and enhances glucose uptake in peripheral tissues, making it a crucial factor in maintaining blood glucose stability

3.3 Tirzepatide effects: cardiovascular, renal, hepatic, and other metabolic effects of tirzepatide Due to concerns that type 2 diabetes medications increased cardiovascular risk, the FDA issued guidance for pharmaceutical companies to perform cardiovascular outcomes trials for new diabetes medications

Mean changes in HbA1c and BW were assessed overall and stratified by diabetes duration, sex, age, baseline body mass index (BMI), baseline estimated glomerular filtration rate (eGFR), and prior dipeptidyl peptidase four inhibitors (DPP4i) use

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