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The internal standard (IS) mixture spiked into each sample prior to analysis and used for normalization consisted of 25 g/mL of TG (15:0)3, PC (17:0)2, PG (14:0)2, lysoPC (20:0), and FA (18:1), Cer (18:01/17) and Cholesteryl ester (17:0)
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To date, regulatory reviews by the MHRA and EMA have found no confirmed causal relationship between semaglutide and pancreatic cancer, though ongoing pharmacovigilance and patient monitoring remain essential
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