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A number of drugmakers are now trialing obesity drugs in combination with various muscle-preserving drugs
In 2023, tirzepatide under the name Zepbound was FDA-approved for obesity as well, after showing ~48 lbs (~22%) mean weight loss over 72 weeks in a trial (SURMOUNT-2) ( [137] )
Zhu X-X, Feng Z-H, Liu L-Z, Zhang Y
Ard J, Lee CJ, Gudzune K, et al
Mild nausea was reported in 23 (32%) VK2735-treated subjects compared with 11% among placebo subjects
