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So what does the evidence say

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As opposed to the small population of GLP1-expressing endocrine cells, the fact that a large part of the pancreatic acinar population expresses GLP1R, even in low density, indicates that there is a considerable amount of nonendocrine GLP1R in the pancreas, for which a physiological role is not yet known

McIntyre explains why psychiatrys spotlight is moving from simple neurotransmitter theories to brain energy and cellular metabolism, and how GLP-1s might aid mood both indirectly (better metabolic health) and directly (GLP-1 action in brain circuits)

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