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The FDA ended shortage-related compounding in 2025 and, on April 30, 2026, proposed keeping tirzepatide off the 503B bulks list permanently

"It makes me nervous if I cant get medicine that improves my quality of life," she said

Physical Effects Increased heart rate Restlessness Jitteriness Sleep disruption Mental and Emotional Effects Heightened anxiety Irritability Difficulty focusing Feeling wired but tired These symptoms are often mistaken for medication issues when they may actually be related to caffeine intake

The results suggest that taste change is far from uncommon