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This study found that, in the realworld, patients treated with semaglutide 2.4 mg had a mean change of 10.5 kg or 10% of body weight from baseline to the end of the 6month followup period, corresponding to a BMI reduction of 3.7 kg/m 2

[30] Among other things, gut dysbiosis can cause intestinal permeability , a condition where toxic byproducts of cellular metabolism called lipopolysaccharides leak out of the gut and into the bloodstream, causing metabolic endotoxemia and chronic, systemic inflammation

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