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mTOR: mammalian target of rapamycin

They also lead to significant loss of muscle mass

A group of researchers, including oncologists and data scientists, from the University of Florida and Indiana University hypothesized that GLP-1s hold promise in oncology due to their ability to lower glucose, adiposity, insulin resistance, and systemic inflammation factors associated with cancer progression, according to a July 2025 paper published in JAMA

In line with this, the gastric emptying delay induced by GLP-1RAs is dependent on the presence of GLP-1Rs on these vagal afferents (Imeryuz et al., 1997)